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Aimone, J

Through receptor mediated signaling, Cagrilintide modulates pathways linked to appetite signaling circuits, gastrointestinal regulatory mechanisms, and broader metabolic feedback systems examined in controlled experimental models

In parallel, chronic ethanol exposure in mice impairs dendritic cell presentation of exogenous antigens through MHC II and alters costimulatory profiles, leading to diminished antigenspecific Tcell activation despite largely preserved MHC I crosspresentation (54)

Nature 447 : 178182

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