Como punto de partida, la Alianza Internacional de Asociaciones de Suplementos Alimentarios (IADSA, en sus siglas inglesas) present en 2007 un informe en el que cita los estudios cientficos que se han realizado para determinar las dosis de seguridad de nutrientes como glucosalina, omega-3, creatina, coenzima Q-10, condroitina, carnitina, lutena y licopeno
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The mean changes from baseline to Week 26 for fasting serum glucose were -32 mg/dL, -16 mg/dL and -27 mg/dL, and for body weight were -2.3 kg, -0.8 kg and +2.8 kg for BYDUREON, sitagliptin, and pioglitazone, respectively