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While the patient groups did not differ by sex, M/M were of slightly lower age relative to both HC and SA and, unsurprisingly, higher fractional exhaled nitric oxide (FeNO) and lower FEV 1 (% predicted) were observed across groups from HC to SA

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doi: 10.1038/s41589-020-0613-y 51 KoppulaPZhuangLGanB

The inhibitor rapamycin can disrupt the proliferation process by suppressing S6 kinase activation