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Its ability to reduce oxidative damage and enhance mitochondrial efficiency also provides neuroprotective benefits, which may slow the progression of neurodegenerative diseases like Alzheimers and Parkinsons

Despite the antitumor effect of erastin, evidence has also shown that iron concentration and macrophage polarization in the tumor microenvironment promote the resistance of ovarian cancer cells to erastin-induced ferroptosis

Anisonyan, E

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Sci Rep 7(1):2383