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Some ophthalmic trials extended treatment to 12 weeks at 4mg daily without safety issues

[DOI] [PMC free article] [PubMed] [Google Scholar] Mats JM, Prez-Gmez C, Nez de Castro I

In addition to phagocytosis, they can secrete bactericidal granule contents after direct activation by the pathogen, either by cytolysis, exocytosis, or piecemeal degranulation (36)

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However, the RDA varies significantly based on age and life stage: Pregnant women: 2.6 mcg/day Breastfeeding women: 2