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[1] [2] It works by mimicking the naturally occurring hormone GLP-1, which regulates appetite and food intake by acting on receptors in the brain, pancreas, and gastrointestinal tract

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Weight Regain Risk After Skipping Doses Research from semaglutide clinical trials shows that patients who maintain consistent dosing lose an average of 1015% of body weight over 68 weeks, while those with lapses in adherence see slower or stalled progress