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Hepatic cytochrome P450 enzyme activity and renal clearance efficiency both decline with age, which could theoretically extend the dihexa half life in older subjects, but specific pharmacokinetic data stratified by age are not published for dihexa

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114 , 382 , 383 , 384 , 385 , 386 , 387 Social inequality and the resulting differences in social and physical environments may directly influence dementia risk among historically marginalized and socially disadvantaged racial and ethnic groups

Attenuation of fear-conditioned analgesia in rats by monoacylglycerol lipase inhibition in the anterior cingulate cortex: potential role for CB(2) receptors