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Chilling injury resulting from LT stress is associated with disparity between making and elimination of ROS

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Consequently, we analyzed three sets of publicly available ADR or MES gene signatures (Supplementary data S1): the Integrated (Int) ADR signature and Int MES signature 12 , which integrate six established signatures from different sources (cells lines, PDXs, and patient tumors)

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"Depletion of phospholipid hydroperoxide glutathione peroxidase up-regulates arachidonate metabolism by 12S-lipoxygenase and cyclooxygenase 1 in human epidermoid carcinoma A431 cells"