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The frequency of B12 shots varies based on individual needs

doi: 10.1016/s0047-6374(97)01897-6

Wash your hands and fingernails with soap and warm water for no less than 20 seconds

Maintenance doses are typically given monthly, but some people may require injections every few months

As clinical signs of cobalamin deficiency include chronic wasting or failure to thrive, malaise, and gastrointestinal signs such as diarrhea, serum cobalamin concentration should be measured in any dog with poor response to enzyme replacement therapy for EPI