5-Amino-1MQ is a substrate-mimetic inhibitor that occupies the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)
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AOD-9604 Assay Design Considerations When incorporating AOD-9604 into a new lipolysis assay, researchers commonly include vehicle controls, a well-characterized positive control such as isoproterenol, and a dose range spanning two to three orders of magnitude
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Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency
Harvard Health Publishing, Harvard Medical School