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A: A medical doctor is usually responsible for carrying out the study according to the study protocol

12 , 13 The interconnected nature of obesity and complications such as OSA and OA has been incorporated into recent definitions of obesity in the literature, where it has been recommended that the diagnosis of clinical obesity requires evidence of altered organ or tissue function, or substantial ageadjusted limitations of daily activities

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Women in the clinical trials averaged slightly higher percentage weight loss than men at comparable doses, though both groups showed clinically meaningful results

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