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Dr Nomathemba Chandiwana, chief scientific officer at South Africas Desmond Tutu Health Foundation, and a specialist in obesity, who was not involved in the study, said: This could be very significant for South Africa and many African countries and low and middle-income countries [LMICs] at large where cost has been one of the main barriers to access. She said analysis suggested about 27% of adults worldwide met the criteria for drugs such as semaglutide and importantly, most of those live in LMICs where access to these medicines is extremely limited

Both contain tirzepatide and use the same available weekly dose strengths, but they have different labeled indications and maintenance-dose language

Molecular characterization of perivascular drainage pathways in the murine brain

Gradual tapering with intensive lifestyle focus provides the best chance for maintaining some of the weight loss achieved

Sid Bondurant, Professor Emeritus at the University of Mississippi Medical Center

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