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Phase 2 clinical trials are currently ongoing assessing additional GLP-1 agonists, lixisenatide (NCT03439943), liraglutide (NCT02953665), and semaglutide (NCT03659682) for the treatment of PD [97]
The most surprising finding was that the benefits of GLP-1 extended far beyond the reduction in decompensating events like ascites, variceal bleeding, hepatorenal syndrome and hepatic encephalopathy, particularly altering liver transplantation risk, Dr
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
And the glucagon part doesnt appear to push meaningful high blood sugar in people without diabetes, which was the obvious worry going in, so on the safety profile thats the genuinely reassuring bit