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Statements Author contributions JL: Conceptualization, Resources, Writing original draft, Visualization, Methodology, Writing review & editing, Project administration, Supervision

Similar defects in prostate development are observed in animals with either 5 -reductase-2 or 5 -reductase-2 plus 5 -reductase-1 gene knockout, and in animals treated with specific 5 -reductase inhibitor

In addition, PYC exhibited anticancer activity by modulating cell signaling pathways, inhibiting tumor cell proliferation, inducing apoptosis, and suppressing angiogenesis

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These include numerous drugs and such varied pollutants as petroleum products and pesticides

[DOI] [PMC free article] [PubMed] [Google Scholar] 278.Tian Z, Sun R, Wei H, Gao B