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To minimize this risk, avoid potassium supplements, potassium-based salt substitutes, and high-potassium foods unless your doctor advises otherwise

In STEP-HFpEF, 529 patients with heart failure with preserved ejection fraction and a BMI of 30 or higher received semaglutide 2.4 mg or placebo for 52 weeks

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[9] Additionally, MB can lead to hyperbilirubinemia (elevated bilirubin levels) in newborns or G6PD-deficient patients due to hemolysis

Both medications cause some lean mass loss, but the ratio of fat loss to lean mass loss appears to favor tirzepatide based on available body composition data from the SURMOUNT trials

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