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Since obesity in humans has been associated with chronic inflammation and increased OS, several studies have studied this relationship in dogs [115,116,117,118,119]

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The proposed mechanisms include upregulation of growth hormone receptors in fibroblasts, modulation of the nitric oxide (NO) system for enhanced angiogenesis (new blood vessel growth), and reduction of inflammatory cytokines

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Mass spectra were acquired using a Data Dependent Acquisition mode (DDA) with full scan spectra done in the Orbitrap while fragments ions were generated by Higher energy Collision-induced Dissociation (HCD) and measured in the linear ion trap

BPC-157 peptide is a synthetic peptide consisting of 15 amino acids