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Sattar N, Lee MMY, Kristensen SL, Branch KRH, Del Prato S, Khurmi NS, et al

Understanding semaglutide onset timelines and discontinuation considerations helps researchers who might transition between single and combined protocols

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Patients should be aware that persistent vomiting or diarrhoea can lead to dehydration , and adequate fluid intake is important

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Interruptions and Discontinuation Increase Cardiovascular Risk Moreover, longer discontinuation was progressively associated with elevated MACE risk, with IRRs of 1.14 for one year of discontinuation and 1.22 for two years