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Current guidelines for T2DM management from ADA and The American Association of Clinical Endocrinologists (AACE) were consulted

J Neurosci 2013;33:43294338.ArticlePubMedPMC 70

What to inject: 3.0 mL reconstitution: 15 units once weekly 2.0 mL reconstitution: 10 units once weekly 4.0 mL reconstitution: 20 units once weekly What to expect: Appetite suppression becomes more noticeable

Not recommended for patients with severe GI disease (not studied)

The health effects of long-term use of these medications for weight loss are unknown and still in clinical trials

Combination Approaches Future treatment approaches may combine multiple mechanisms for enhanced efficacy