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Avoid greasy or high-fat foods, especially early in the day

The most common adverse effects are gastrointestinal in nature, including diarrhea, constipation, abdominal cramping, and flatulence

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Its active ingredient, tirzepatide , activates two essential hormonal receptors: GIP and GLP-1

Retatrutide Weight Loss Results Phase 2 trial data published in 2023 showed that retatrutide at the 12 mg dose produced an average weight loss of approximately 24.2% at 24 weeks , with projections suggesting that the loss could approach 2829% at 48 weeks based on the observed trajectory