Antimicrobial Preservatives for Protein and Peptide Formulations: An Overview
Diethyl maleate Based on 1 publication(s) in Google Scholar Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier
It is also used as an anti-inflammatory agent, antioxidant, heavy metal chelator, antiviral drug, vascular permeability regulator, regulator of ATP and NO synthesis, as well as in CNS disorders, cardiovascular diseases, and retinitis pigmentosa
Neurochem J 14(2):127132
Biochim Biophys Acta 5:165664
In murine macrophages, glucocorticoids generally suppress production of pro-inflammatory eicosanoids (e.g., prostaglandins and leukotrienes), and pro-inflammatory cytokines (e.g., IL-1, IL-6, TNF, and IL-12), and they inhibit leukocyte migration (85, 9094)