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If any side effects are experienced, such as irritability, the dose may need to be reduced

Further to this, a dose escalation study with GLP-2 (100, 200, 400, and 800g, single subcutaneous injections) in postmenopausal women revealed dose-dependent reductions of CTX-I levels and related bone resorption, 10 that are believed to be sustainable in nature

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While these medications themselves are not typically known to directly cause spinal pain, rapid body changes can sometimes reveal underlying disc problems or alter how the spine is supported

doi:10.2337/dc13-2761

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