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arsenic contributes to an imbalance between necessary and harmful levels of intracellular hydrogen peroxide as discussed in a review by Nurchi et al (2020)

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The use of Drosophila bring to the study of oxidative liver injury many advantages, including ease of genetic manipulation, availability of genetic mutants and constructs, ease of germ-free generation, relatively short lifespan, amenability to high-throughput screening, and overall cost relative to murine models 40

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