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Many promising laboratory mechanisms fail to translate to meaningful human effects

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These findings are consistent with those of Phusate (2021) who observed a substantial reduction in thyroxine (T4) and triiodothyronine (T3) levels in male rats after 60 days of GLP exposure, along with a non-significant increase in TSH levels compared to the control group

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These findings emphasize the importance of epigenetic modifications in thyroid autoimmunity and suggest that further research may lead to novel diagnostic and nutritional therapeutic approaches [82] (Table 4)