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Bibliography Best, C

Recent literature suggests that central GLP-1 and GIP have a synergistic action on hypothalamic neurons with effects on food intake and body weight (24) ( Figure 2 )

Therefore, when used as an adjunct to intensive behavioral therapy and an initial low-calorie diet, once-weekly subcutaneous semaglutide produced significantly greater weight loss than placebo during 68 weeks in adults with overweight or obesity

At a fixed fill volume a 30mg vial reaches three times the concentration of a 10mg vial, so volumes cannot be carried across vial sizes unchanged

doi: 10.1038/s41591-024-03041-y

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