Serious side effects of the medication include the following: Allergic or hypersensitivity reaction Severe gastrointestinal issues Changes in mood and behavior Pancreatitis Liver problems Low blood sugar levels (hypoglycemia) Cardiac arrhythmias Suicidal ideation Major depressive disorder No adverse event of hypoglycemia or thyroid cancer was reported in Phase II trials, and 7% of retatrutide participants had skin sensitivity, compared to 1% on placebo, but these cases were not serious
It also has to label its products honestly as research-use-only rather than hint at human use
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19 Moreover, although acute pancreatitis and gallbladder disease secondary to tirzepatide were rare in the SURPASS trials, patients should be monitored for signs and symptoms of these issues
But with weekly doses of the drug, the group saw a 41 per cent reduction in the alcoholic drinks they consumed, as well as alcohol cravings dropping by about the same figure