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In spinal cord tissues from patients with ALS, the expression of arachidonate 5-Lipoxygenase (ALOX5) and complement component 3 (C3) was markedly upregulated, accompanied by reduced GSH levels, elevated iron concentrations, and enhanced lipid peroxidation

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Epigenetic downregulation of Scn3a expression by Valproate: a possible role in its anticonvulsant activity

This is the part patients are most often surprised by

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Children (Basel, Switzerland) 2023