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It observed an association between GLP-1 drug use and a small increased incidence of ischemic optic neuropathy but cannot definitively establish that GLP-1 medications cause the condition

Orforglipron was intentionally administered 4 hours earlier because of its partial agonist properties, which mean that it takes longer for it to act

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Lim, S., et al

And so that suggests that theres some overlapping pathways there

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