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The purified non-acylated tirzepatideGIPRmini-G s Nb35 complex at a concentration of 14-16 mg/mL was mixed with 100 M non-acylated tirzepatide at 4 C and applied to glow-discharged holey carbon grids (Quantifoil R1.2/1.3, Au 300 mesh) that were subsequently vitrified by plunging into liquid ethane using a Vitrobot Mark IV (ThermoFisher Scientific)

Drug Design, Development and Therapy, 18, 125138.

We would target this during the next phase of our program

Understanding the mechanistic differences between albuminuric and non-albuminuric DKD enables more tailored therapeutic interventions

FEBS Letters (1988) 12