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For example, in March 2010, the ACA was enacted, which substantially changed the way healthcare is financed by both governmental and private insurers, and significantly affected the pharmaceutical industry

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*Correspondence: Maurizio Delvecchio, [email protected] These authors have contributed equally to this work These authors have contributed equally to this work Deceased Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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