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At least 35 different mutations in the HLCS gene have been found associated with holocarboxylase synthetase deficiency

Lipoic acid, either as a dietary supplement or a therapeutic agent, modulates distinct redox circuits because of its ability to equilibrate between different subcellular compartments as well as extracellularly

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Orthomolecular approaches against radiation exposure

Moreover, both doses of the acylated ligand exerted a larger anti-hyperglycaemic effect in an intra-peritoneal glucose tolerance test performed 72 hours after dosing (Figure 5F)