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doi: 10.1210/en.2012-1937 194 RakipovskiGRolinBNhrJKleweIFrederiksenKSAugustinRet al

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The result is profound orthostatic intolerance, where the simple act of standing up triggers a cascade of debilitating symptoms, including tachycardia, dizziness, and severe shortness of breath, all rooted in a fundamental lack of cellular energy