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doi: 10.1530/rep-23-0070 90 LiteCRajaGLJulietMSridharVVSubhashreeKDKumarPet al

More recently, in CHD patients undergoing PCI, intravenous administration of probucol (500 mg twice daily, one day before and three days after surgery) increased serum GSH levels [244]

In the presence of GST, GSH would conjugate CDNB through thiol group

On the general safety profiles of ICI agents, a head-to-head comparison of 36 phase 1 and phase 2 clinical trials that enrolled 15,370 patients found that the safety ranking of ICIs as follows: Atezolizumab (pooled incidence 66.4%, probability 76%), Nivolumab (71.8%, 56%), Pembrolizumab (75.1%, 55%), Ipilimumab (86.8%, 55%) and Tremelimumab (not applicable (NA), 54%)

Bethesda, MD: American Society of Health-System Pharmacists, 2012 p.3619-3622 9

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