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Medical providers can help people start with the least potent doses and gradually work up to stronger versions of the medications

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.78 2.4, 2~3 .78 2 (T2DM) .79,80 T2DM .81 , .84,85 .86,87,88 2010 FDA T2DM Victoza .83,89,90,91,92 Saxenda .62 34 (GLP-1(7-37)) , 26 16

8 Specifically, the FDA voiced concern about investigational plan deviations to enroll subjects who did not meet eligibility criteria, which jeopardizes subjects safety and welfare and raises concerns about the validity and integrity of the data collected

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Lysates were centrifuged at 14,000 rpm for 15 min, and protein concentration was determined using the BCA kit (Thermo Fisher, 23227)