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Reverse Phase Purification 1 The Example 4A Crude is dissolved in 90 wt % MPA and 10 wt % MPB

Semaglutide 2.4 mg produced 14.9% at 68 weeks in STEP 1

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Based on our prior experience, 22 NanoBiT strategy 23,24 was used in this study to stabilize the GLP-2GLP-2RG s complex and strengthen the interactions between GLP-2R and G, resulting in a cryo-EM structure at a global resolution of 3.0 (Supplementary information, Table S1)

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