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Researchers have observed this protective effect through glutathiones activation of the Nrf2/HO-1 signaling pathway [4]

Results showed: Significant increase in skin density and thickness Measurable reduction in fine line depth (up to 35% in some cohorts) Improved skin laxity and elasticity scores Enhanced skin moisture retention These effects are largely attributed to GHK-Cus ability to stimulate fibroblast activity the cells responsible for producing collagen type I and III, elastin, and hyaluronic acid

Table 1 summarises the characteristics of the included studies

Benchenane, K

The letter L refers to the amino-acid configuration