Insert the needle at a 90-degree angle straight into the pinched skin
Back Holst, JJ (26 April 2019) 'From the Incretin Concept and the discovery of GLP-1 to today's diabetes therapy', Frontiers in Endocrinology , 10
This matters because muscle supports strength, balance, glucose handling, metabolism, mobility, and long-term weight maintenance
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The starting dose in clinical trials is 1 mg once weekly
During the first week, its normal to experience a gradual reduction in hunger and an increase in feelings of fullness, but the appetite-suppressing effects may take some time to become fully apparent