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Your dose of Synjardy XR will depend on your current medications whether youre currently taking either Jardiance (empagliflozin), metformin, or both Dosing for people who currently arent taking either Jardiance (empagliflozin) or metformin is listed below Synjardy Adults and children 10 years and older: The typical dose ranges from 5 mg/500 mg (empagliflozin / metformin) to 12.5 mg/1,000 mg (empagliflozin / metformin) by mouth twice daily with food