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using transplantation of wild-type (WT) neurons, found that A entered WT grafts accompanied by microglia infiltration and in vivo imaging revealed that microglia were carries of A pathology in previously unaffected tissue 154 (Fig

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Enzymatic activity was evaluated through a colorimetric assay where DTNB is reduced with NADPH to become TNB in an assay catalyzed by TrxR