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1 Introduction Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age, with a global prevalence of approximately 10%13%

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How the Gila monster led to the first GLP-1 drug NIDDK scientists reported in 1992 that exendin-4 could lower glucose in animal models, and later trials confirmed similar effects in humans

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This system, responsible for the degradation of damaged and unnecessary proteins through ubiquitin-mediated mechanisms, regulates numerous fundamental cellular processes

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