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The final fate of intracellular meningococci is largely unknown, but it has been found that GPB1, mediating the initial assembly of GBP platform on cytosolic Gram-negative intracellular bacteria, and GBP3, a component of the GBPs recruited to the platform for caspase-4 activation, selectively lyse F

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It's the failure to account for reconstitution ratios, which determine actual peptide concentration per injection volume

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