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It says recent GLP-1 trials documented reflux as an adverse event in 5-15% of participants, with severity varying widely, and that real-world data suggests higher rates among people who already had GERD

This accelerated mtDNA aging phenotype is associated with frailty, multimorbidity, and potentially shorter lifespan (125, 147, 148)

Researchers comparing analogs should understand where each fits in the experimental toolkit

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Tirzepatide significantly improves glycemic control in individuals with type 2 diabetes or prediabetes