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A rational protocol is kisspeptin daily for ongoing hormonal optimization, with PT-141 as-needed for acute libido enhancement

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FIGURE 2 3.3 Anti-cell proliferation and pro-apoptosis effects 3.3.1 p53-dependent cell cycle control and apoptosis p53 is a crucial gene that regulates the balance between cell proliferation and apoptosis through a variety of routes by activating its target genes p21 Waf1/Cip1 and BCL2-associated X protein (Bax)-1

(Pheo)melanin photosensitizes UVA-induced DNA damage in cultured human melanocytes