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Learnings from this initial 3-year phase will inform the rollout to a wider group of eligible patients over a maximum period of 12 years

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Innovative drugs that target several pathways connected to SCD pathogenesis have emerged as a consequence of collaboration between the government (National Institutes of Health), industry, and academia

GSH can also serve as a substrate for S-glutathionylation of proteins in the presence of small redox enzyme glutaredoxins (GRX), which also utilizes GSH as a cofactor ( Figure 1 )

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