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After 12 months of use, 58% of patients achieved a BMI reduction 5%, 35% achieved a BMI reduction 10%, and 17% achieved a BMI reduction 15%

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Absence of TIMP4 ameliorated high-fat-diet-induced obesity in mice 30

Patients with UQCC2 mutations may experience generalized seizures and status epilepticus, with EEG findings showing low-voltage activity (90, 91)