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If a pharmacy refuses your replacement request, escalate to a supervisor

Approximately equal numbers of patients were randomized to receive placebo, 100 mg of sitagliptin once daily, 500 mg or 1000 mg of metformin HCl twice daily, or 50 mg of sitagliptin twice daily in combination with 500 mg or 1000 mg of metformin HCl twice daily

This stepwise approach can be the most cost-effective strategy. Switching from semaglutide to liraglutide is also an option, particularly when side effects are impacting the patients overall health

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Side effects are the typical symptoms associated with menopause and some additional concerns

J R Stat Soc Series B Stat Methodol