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GLP-1 and GLP-2 Orchestrate intestine integrity, gut microbiota, and immune system crosstalk

Together, they orchestrate a crucial hormonal regulation known as the incretin effect

Comparison of treatments was performed on a within-subject level (each mouse was its own control) and at least 1 week elapsed between each testing condition (drug or control treatment)

However, this inhibitory effect is significantly weakened in patients with T2DM, indicating that its potential application in diabetes treatment requires further investigation

2022;34(1):59-74.e10

Correction of HR estimates and 95% CI for bias due to outcome misclassification was carried out according to the Brenner and Gefellers methodology [25]