The compound has been studied in preclinical and clinical research as a selective MC3R/MC4R melanocortin receptor agonist, with research focus on melanocortin-mediated pathway biology in reproductive research models (Hadley, 2005 PMID: 15849413)
Acknowledgements This open-access review paper was supported by The project New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM, project ID CZ.02.01.01/00/22_008/0004607, is co-funded by the European Union, and the Erasmus+ Programme of the European Union, Key Action 2: Strategic Partnerships, Project no
Abstract We revealed the therapy effect of the stable gastric pentadecapeptide BPC 157 (10 g/kg, 10 ng/kg ig or po) with specific activation of the collateral rescuing pathways, the azygos vein, on bile duct ligation in particular, and acute pancreatitis as local disturbances (i.e., improved gross and microscopy presentation, decreased amylase level)
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It boosts erythropoiesis by attaching to its receptor, which is found on the surface of erythroid progenitor cells
doi:10.1016/j.jinorgbio.2013.04.002