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Nutrition, 31 (6), 781-786

While the research showed these supplements can increase NAD+ levels in the body, the studies did not show clear evidence that these increases lead to meaningful health benefits.For instance, one study involving 33 patients with heart failure examined whether supplementing with NR could help slow worsening cardiac function, which had previously been observed in animal models

Lima FB, Machado UF, Bartol I, et al

Refrigeration (2-8C / 36-46F): The Standard Protocol This is the sweet spot

The assay was performed in accordance with the manufacturers instructions

A multi-year study addressed this question