FASEB J 2010;24:587598.ArticlePubMed 19
The soaring demand for GLP-1 drugs, shorthand for glucagon-like peptide-1 receptor agonists, may be shifting attitudes about what it means to be overweight, experts say
Who are GLP-1 weight-loss medications for
Research dosing (clinical settings only): Self-administration of kisspeptin outside clinical supervision is not recommended due to the need for precise weight-based dosing and IV/SubQ technique
The exceptions: PT-141 for women uses 1.75 mg subcutaneously (the FDA-approved Vyleesi dose), which differs from the research doses listed for men
Decreasing Hunger and Increasing Satiety Many weight loss drugs of the past had questionable results, but semaglutide, tirzepatide, and orforglipron may be game changers for weight management