Why Your B12 Shots Are Not Working Vitamin B12 and vitamin b12 shots have a long list of potential health improvement claims from low energy to neuropathy
In this study, we observed a positive correlation between changes in serum GSSG levels and reductions in both the total PANSS scores and positive symptom scores among ECT responders, suggesting that the redox state changes correspondingly with the improvement to clinical symptoms
10.1017/s1355617710000196 J
This matters for a supplement intended for daily long-term use.* How does creatine support cognitive function
Epidemiologic studies have shown a link between vitamin B12 and folate deficiencies and increased metabolic risk
Common Causes and Contributors: From Vascular to Medication Effects When I assess ED, I use a structured framework: Vascular (vasculogenic) Atherosclerosis, endothelial dysfunction, impaired NO signaling Diabetes-related microvascular disease Hypertension-related vascular remodeling Neurogenic Peripheral neuropathy (diabetes, B12 deficiency, chemotherapy) Post-surgical or post-radiation nerve injury (e.g., radical prostatectomy) Spinal stenosis, discopathy, or pelvic nerve entrapment Hormonal Low testosterone (hypogonadism): impacts libido and PDE5 responsiveness Thyroid dysfunction, hyperprolactinemia, cortisol dysregulation Aromatization and unfavorable T:E2 ratios Psychogenic Depression, anxiety, relationship stress, sexual trauma history Performance anxiety and maladaptive autonomic patterns Drug-induced Antihypertensives (e.g., beta blockers, thiazides) SSRIs/SNRIs, antipsychotics Opioids and androgen suppression Iatrogenic and trauma-related Pelvic surgeries, radiation fibrosis Pelvic fractures, lumbar/pelvic injuries Lifestyle and sleep Sedentary behavior, obesity, poor diet, alcohol use Sleep apnea (major factor in testosterone and endothelial dysfunction) Biomechanics and pain Pelvic floor hypertonicity or dyssynergia SI joint dysfunction, lumbar facet syndromes, hip pathology This framework helps us prioritize diagnostics and personalize treatment
